Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.68 extracted from

  • Butenas, S.; Kalafatis, M.; Mann, K.G.
    Analysis of tissue plasminogen activator specificity using peptidyl fluorogenic substrates (1997), Biochemistry, 36, 2123-2131.
    View publication on PubMed
Search for more literature for 3.4.21.68

Cloned(Commentary)

Cloned (Comment) Organism
recombinant tPA from Genentech, 80% sc-tPA, 20% tc-tPA Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00022
-
 D-FPRANSNH-i-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0003
-
 D-VPRANSNH-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0003
-
 D-LPRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.00037
-
 D-FPRANSN-C2H5-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.00038
-
 D-FPRANSN-(CH2)6 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0004
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0004
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0004
-
 Boc-D-LGRANSNH-C6H11 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0004
-
 D-FPRANSNH-C6H5CH2 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0004
-
 D-FPRANSNH-n-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0004
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.00046
-
 D-FPR-ANSNH-CH2COOCH3 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0005
-
 Boc-D-VPR-ANSNHC4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.00059
-
 D-FPRANSNH-c-C6H11 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0006
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0006
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0007
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.00078
-
 D-FPR-ANSNH-C2H4OCH3 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0008
-
 Boc-D-FLRANSNHC3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.001
-
 D-LGRANSNH-C6H11 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0011
-
 D-FVRANSNH-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0011
-
 D-FPRANSNH-t-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0012
-
 D-LSRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0015
-
 D-VGRANSNH-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0026
-
 Boc-D-FPRANSNH-C6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.0027
-
 Boc-D-FVRANSNH-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.0057
-
 D-FPRANSNH-C6H11 pH 7.4, 25°C, sc-tPA Homo sapiens
0.0066
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.0073
-
 D-FVRANSNH-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.0074
-
 D-FLRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.0078
-
 D-FVRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.0081
-
 D-VPRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.0085
-
 Boc-D-LGRANSNH-C6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.0088
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.01
-
 D-FLRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.011
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.011
-
 D-LGRANSNH-C6H11 pH 7.4, 25°C, tc-tPA and sc-tPA Homo sapiens
0.012
-
 Boc-D-FVRANSNH-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.012
-
 D-LPRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.013
-
 D-FPRANSNH-C6H11 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.013
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.013
-
 Boc-D-FLRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.014
-
 D-LSRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.014
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.015
-
 Boc-D-LGRANSNH-C6H11 pH 7.4, 25°C Homo sapiens
0.015
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.015
-
 Boc-D-VPRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.016
-
 D-FVRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
0.016
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.017
-
 Boc-D-FLRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.017
-
 D-LSRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.019
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.02
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.022
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.023
-
 Boc-D-LGRANSNH-C6H11 pH 7.4, 25°C, sc-tPA Homo sapiens
0.025
-
 D-VPRANSNH-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.025
-
 D-FPRANSNH-C6H5CH2 pH 7.4, 25°C, tc-tPA Homo sapiens
0.026
-
 Boc-D-VPRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.026
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.029
-
 Boc-D-VPRANSNH-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.029
-
 D-FPRANSNH-CH2COOCH3 pH 7.4, 25°C, tc-tPA Homo sapiens
0.03
-
 Boc-D-FLRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.032
-
 Boc-D-FVRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.033
-
 D-VGRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.036
-
 L-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
0.04
-
 D-LPRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.041
-
 D-LGRANSNH-C6H11 pH 7.4, 25°C Homo sapiens
0.047
-
 Boc-D-FPRANSNH-C6H11 pH 7.4, 25°C Homo sapiens
0.048
-
 D-FPRANSNH-n-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.058
-
 D-VGRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.063
-
 D-FPRANSNH-CH2COOCH3 pH 7.4, 25°C, sc-tPA Homo sapiens
0.063
-
 D-FPRANSNH-C6H5CH2 pH 7.4, 25°C, tc-tPA Homo sapiens
0.065
-
 plasminogen pH 7.4, 37°C Homo sapiens
0.066
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.069
-
 D-LSRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.071
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
0.074
-
 D-FPRANSNH-i-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.077
-
 D-FPRANSNH-C6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.079
-
 D-FPRANSNH-t-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.084
-
 D-FPRANSNH-t-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.088
-
 D-FPRANSNH-c-C6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.091
-
 Boc-D-FVRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
0.095
-
 D-FPRANSNH-n-C6H13 pH 7.4, 25°C, tc-tPA Homo sapiens
0.096
-
 D-FPRANSNH-n-C6H13 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.096
-
 D-FPRANSN-(CH2)6 pH 7.4, 25°C, tc-tPA Homo sapiens
0.098
-
 D-LPRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.099
-
 D-FPR-ANSNH-n-C6H13 pH 7.4, 25°C, sc-tPA Homo sapiens
0.1
-
 Boc-L-VGRANSNHC4H9 pH 7.4, 25°C Homo sapiens
0.11
-
 D-VPRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.12
-
 D-FPRANSNH-n-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.12
-
 D-FPRANSN-C2H5-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.14
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.14
-
 D-FPRANSNH-C2H4OCH3 pH 7.4, 25°C, tc-tPA Homo sapiens
0.15
-
 D-FPRANSNH-c-C6H11 pH 7.4, 25°C, sc-tPA Homo sapiens
0.18
-
 D-FPRANSNH-C2H4OCH3 pH 7.4, 25°C, tc-tPA Homo sapiens
0.25
-
 D-FPRANSN-(CH2)6 pH 7.4, 25°C, sc-tPA Homo sapiens
0.32
-
 D-FPRANSN-C2H5-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.33
-
 D-FPRANSNH-i-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.36
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.39
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
0.46
-
 L-VGRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.97
-
 L-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
plasminogen + H2O Homo sapiens
-
 plasmin + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(p-F)-FPRANSNH-C2H5 + H2O
-
 Homo sapiens (p-F)-FPR + ANSNH-C2H5
-
 ?
Boc-(p-F)-FPRANSNH-C2H5 + H2O
-
 Homo sapiens Boc-(p-F)-FPR + ANSNH-C2H5
-
 ?
Boc-D-FLRANSNH-C3H7 + H2O
-
 Homo sapiens Boc-D-FLR + ANSNH-C3H7
-
 ?
Boc-D-FPRANSNH-C6H11 + H2O
-
 Homo sapiens Boc-D-FPR + ANSNH-C6H11
-
 ?
Boc-D-FVRANSNH-C2H5 + H2O
-
 Homo sapiens Boc-D-FVR + ANSNH-C2H5
-
 ?
Boc-D-LGRANSNH-C6H11 + H2O
-
 Homo sapiens Boc-D-LGR + ANSNH-C6H11
-
 ?
Boc-D-LPRANSNH-C3H7 + H2O
-
 Homo sapiens Boc-D-LPR + ANSNH-C3H7
-
 ?
Boc-D-LSRANSNH-C3H7 + H2O
-
 Homo sapiens Boc-D-LSR + ANSNH-C3H7
-
 ?
Boc-D-VGRANSNH-C4H9 + H2O
-
 Homo sapiens Boc-D-VGR + ANSNH-C4H9
-
 ?
Boc-D-VPRANSNH-C4H9 + H2O
-
 Homo sapiens Boc-D-VPR + ANSNH-C4H9
-
 ?
Boc-L-FPRANSNH-C2H5 + H2O
-
 Homo sapiens Boc-L-FPR + ANSNH-C2H5
-
 ?
Boc-L-VGRANSNH-C4H9 + H2O
-
 Homo sapiens Boc-L-VGR + ANSNH-C4H9
-
 ?
D-FLRANSNH-C3H7 + H2O
-
 Homo sapiens D-FLR + ANSNH-C3H7
-
 ?
D-FPR ANSNH-C6H11 + H2O
-
 Homo sapiens D-FPR + ANSNH-C6H11
-
 ?
D-FPRANSN-(CH2)6 + H2O
-
 Homo sapiens D-FPR + ANSN-(CH2)6
-
 ?
D-FPRANSN-C2H5 + H2O
-
 Homo sapiens D-FPR + ANSN-C2H5
-
 ?
D-FPRANSN-C2H5-C2H5 + H2O
-
 Homo sapiens D-FPR + ANSN-C2H5-C2H5
-
 ?
D-FPRANSNH-c-C6H11 + H2O
-
 Homo sapiens D-FPR + ANSNH-c-C6H11
-
 ?
D-FPRANSNH-C2H4OCH3 + H2O
-
 Homo sapiens D-FPR + ANSNH-C2H4OCH3
-
 ?
D-FPRANSNH-C6H5CH2 + H2O
-
 Homo sapiens D-FPR + ANSNH-C6H5CH2
-
 ?
D-FPRANSNH-CH2COOCH3 + H2O
-
 Homo sapiens D-FPR + ANSNH-CH2COOCH3
-
 ?
D-FPRANSNH-i-C3H7 + H2O
-
 Homo sapiens D-FPR + ANSNH-i-C3H7
-
 ?
D-FPRANSNH-n-C4H9 + H2O
-
 Homo sapiens D-FPR + ANSNH-n-C4H9
-
 ?
D-FPRANSNH-n-C6H13 + H2O
-
 Homo sapiens D-FPR + ANSN-H-n-C6H13
-
 ?
D-FPRANSNH-t-C4H9 + H2O
-
 Homo sapiens D-FPR + ANSNH-t-C4H9
-
 ?
D-FVRANSNH-C2H5 + H2O
-
 Homo sapiens D-FVR + ANSNH-C2H5
-
 ?
D-LGRANSNH-C6H11 + H2O
-
 Homo sapiens D-LGR + ANSNH-C6H11
-
 ?
D-LPRANSNH-C3H7 + H2O
-
 Homo sapiens D-LPR + ANSNH-C3H7
-
 ?
D-LSRANSNH-C3H7 + H2O
-
 Homo sapiens D-LSR + ANSNH-C3H7
-
 ?
D-VGRANSNH-C4H9 + H2O
-
 Homo sapiens D-VGR + ANSNH-C4H9
-
 ?
D-VPRANSNH-C4H9 + H2O
-
 Homo sapiens D-VPR + ANSNH-C4H9
-
 ?
L-FPRANSN-C2H5 + H2O
-
 Homo sapiens L-FPR + ANSN-C2H5
-
 ?
L-VGRANSNH-C4H9 + H2O
-
 Homo sapiens L-VGR + ANSNH-C4H9
-
 ?
additional information single-chain t-PA, sct-PA can be converted to two-chain forrm, tct-PA, by activation cleavage at the arg275-Ile276 peptide bond, no hydrolysis of Boc-L-FLRANSNH-C3H7, L-FLRANSNH-C3H7, Boc-D-VSRANSNH-(i-C3H7), D-VSRANSNH-(i-C3H7), BOC-D-VLRANSN-H4H9, D-VLRANSN-H4H9, Boc-D-PGRANSNH-(i-C3H7), D-PGRANSNH-(i-C3H), Boc-D-PPRANSNH-(i-C3H7), D-PPRANSNH-(i-C3H7), Boc-D-SPRANSNH-CH2C6H5, D-SPRANSNH-CH2C6H5, Boc-L-SPRANSNH-CH2C6H5, L-SPRANSNH-CH2C6H5, Boc-L-(Obz)SPRANSNH-CH2C6H5, L-(Obz)SPRANSNH-CH2C6H5, (Z)-L-(Boc)EGRANSNH-C3H7, (Z)-L-EGRANSNH-CH7, L-EGRANSNH-C3H7, (Z)-L-(Boc)EPRANSNH-C3H7, (Z)-L-EPR-ANSNH-C3H7, and L-EPRANSNH-C3H7 Homo sapiens ?
-
 ?
plasminogen + H2O
-
 Homo sapiens plasmin + ?
-
 ?

Synonyms

Synonyms Comment Organism
sc-tPA single-chain Homo sapiens
tc-tPA two-chain Homo sapiens
Tissue plasminogen activator
-
 Homo sapiens
Tissue-type plasminogen activator
-
 Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.0084
-
 D-LGRANSNH-C6H11 pH 7.4, 25°C, sc-tPA Homo sapiens
0.01
-
 Boc-D-FLRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.011
-
 D-FVRANSNH-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.012
-
 Boc-D-LGRANSNH-C6H11 pH 7.4, 25°C, sc-tPA Homo sapiens
0.016
-
 D-FPR-ANSNH-C6H11 pH 7.4, 25°C, sc-tPA Homo sapiens
0.017
-
 Boc-D-FPRANSNH-C6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.018
-
 D-FLRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.019
-
 D-LSRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.019
-
 Boc-D-FVRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.021
-
 Boc-D-FLRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.021
-
 D-VGRANSNH-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.022
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.025
-
 D-FVR-ANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.034
-
 D-LGR-ANSNH-C6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.036
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.038
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.04
-
 L-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
0.04
-
 Boc-D-LGRANSNH-C6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.044
-
 Boc-D-FVRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
0.047
-
 Boc-D-FLRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.057
-
 D-LGRANSNH-C6H11 pH 7.4, 25°C Homo sapiens
0.059
-
 D-VPRANSNH-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.061
-
 D-LPRANSNH-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.065
-
 Boc-D-VPRANSNH-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.08
-
 L-VGRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.082
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.083
-
 D-FPRANSNH-CH2COOCH3 pH 7.4, 25°C, sc-tPA Homo sapiens
0.084
-
 Boc-L-VGRANSNHC4H9 pH 7.4, 25°C Homo sapiens
0.09
-
 D-FPRANSN-C2H5-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.097
-
 Boc-D-LGRANSNH-C6H11 pH 7.4, 25°C Homo sapiens
0.097
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.099
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.1
-
 Boc-D-FLRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.1
-
 D-LSRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.11
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.13
-
 D-FPRANSN-(CH2)6 pH 7.4, 25°C, sc-tPA Homo sapiens
0.14
-
 D-FPRANSN-C2H5-C2H5 pH 7.4, 25°C, sc-tPA Homo sapiens
0.15
-
 Boc-D-FPRANSNH-C6H11 pH 7.4, 25°C Homo sapiens
0.15
-
 D-FPRANSN-H-c-C6H11 pH 7.4, 25°C, sc-tPA Homo sapiens
0.15
-
 Boc-D-FVRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.15
-
 D-FPRANSNH-CH2COOCH3 pH 7.4, 25°C, tc-tPA Homo sapiens
0.16
-
 D-VPRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.17
-
 D-LPRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.18
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.19
-
 D-VGRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.2
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.2
-
 D-FPRANSN-H-i-C3H7 pH 7.4, 25°C, tc-tPA Homo sapiens
0.22
-
 D-FPRANSN-(CH2)6 pH 7.4, 25°C, tc-tPA Homo sapiens
0.25
-
 Boc-D-VPRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.25
-
 D-FPRANSN-H-t-C4H9 pH 7.4, 25°C, sc-tPA Homo sapiens
0.25
-
 Boc-D-VPRANSNH-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.27
-
 D-FPRANSNH-C2H4OCH3 pH 7.4, 25°C, sc-tPA Homo sapiens
0.29
-
 D-FPRANSNH-i-C3H7 pH 7.4, 25°C, sc-tPA Homo sapiens
0.31
-
 D-LPRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.32
-
 D-FPRANSNH-c-C6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.33
-
 D-FPRANSNH-n-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.34
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.37
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.44
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, tc-tPA Homo sapiens
0.45
-
 D-FPR-ANSNH-C6H5CH2 pH 7.4, 25°C, sc-tPA Homo sapiens
0.47
-
 D-FPR-ANSNH-n-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
0.49
-
 Boc-D-FVRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
0.51
-
 D-FPR-ANSNHC6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
0.53
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.54
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
0.54
-
 D-FPRANSNH-C6H5CH2 pH 7.4, 25°C, tc-tPA Homo sapiens
0.66
-
 D-FPRANSNH-C2H4OCH3 pH 7.4, 25°C, tc-tPA Homo sapiens
0.69
-
 D-FPRANSNH-i-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
0.7 1 D-VPRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.71
-
 D-VPRANSNH-C4H9 pH 7.4, 25°C Homo sapiens
0.94
-
 D-FPRANSN-H-t-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
1.03
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
1.1
-
 D-FPRANSNH-n-C6H13 pH 7.4, 25°C, sc-tPA Homo sapiens
1.2
-
 D-FPRANSNH-C6H5CH2 pH 7.4, 25°C, ratio tc/sc Homo sapiens
1.4
-
 D-FPRANSNH-n-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
1.47
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
1.6
-
 D-FPRANSN-C2H5-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
1.7
-
 D-FPRANSN-(CH2)6 pH 7.4, 25°C, ratio tc/sc Homo sapiens
1.8
-
 D-FPRANSNH-CH2COOCH3 pH 7.4, 25°C, ratio tc/sc Homo sapiens
2.1
-
 D-FPRANSNH-c-C6H11 pH 7.4, 25°C, ratio tc/sc Homo sapiens
2.3
-
 D-FVRANSNH-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
2.4
-
 D-FPRANSNH-C2H4OCH3 pH 7.4, 25°C, ratio tc/sc Homo sapiens
2.7
-
 D-VPRANSNH-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
2.8
-
 D-LPRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
3.3
-
 Boc-D-LGRANSNH-C6H11 pH 7.4, 25°C, ratio tc/sc Homo sapiens
3.3
-
 D-FPR-ANSNH-n-C6H13 pH 7.4, 25°C, ratio tc/sc Homo sapiens
3.6
-
 D-FPR-ANSNH-n-C6H13 pH 7.4, 25°C, tc-tPA Homo sapiens
3.7
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
3.8
-
 Boc-D-VPRANSNH-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
3.8
-
 D-FPR-ANSNH-t-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
4
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
4
-
 D-LGR-ANSNH-C6H11 pH 7.4, 25°C, ratio tc/sc Homo sapiens
4.4
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
4.7
-
 Boc-D-FLRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
5
-
 Boc-D-VGRANSNH-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
5.3
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
5.3
-
 D-LSRANSNH-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
6.08
-
 Boc-(p-F)-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
6.08
-
 (p-F)-FPRANSNH-C2H5 pH 7.4, 25°C Homo sapiens
6.08
-
 Boc-D-LSRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
6.08
-
 Boc-D-LPRANSNH-C3H7 pH 7.4, 25°C Homo sapiens
6.08
-
 D-FPRANSNH-i-C3H7 pH 7.4, 25°C, ratio tc/sc Homo sapiens
6.08
-
 D-FPRANSNH-C6H5CH2 pH 7.4, 25°C, tc-tPA Homo sapiens
6.08
-
 D-FPRANSNH-C2H4OCH3 pH 7.4, 25°C, tc-tPA Homo sapiens
6.08
-
 D-FPRANSN-H-t-C4H9 pH 7.4, 25°C, tc-tPA Homo sapiens
6.08
-
 D-FPR-ANSNHC6H11 pH 7.4, 25°C, tc-tPA Homo sapiens
7.9
-
 Boc-D-FVR-ANSNH-C2H5 pH 7.4, 25°C, ratio tc/sc Homo sapiens
9
-
 D-VGRANSNH-C4H9 pH 7.4, 25°C, ratio tc/sc Homo sapiens
32
-
 D-FPRANSNH-C6H11 pH 7.4, 25°C, ratio tc/sc Homo sapiens
89
-
 D-LSRANSNHC3H7 pH 7.4, 25°C Homo sapiens