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Literature summary for 3.4.21.68 extracted from

  • Loskutoff, D.J.; Schleef, R.R.
    Plasminogen activators and their inhibitors (1988), Methods Enzymol., 163, 293-302.
    View publication on PubMed
Search for more literature for 3.4.21.68

Activating Compound

Activating Compound Comment Organism Structure
Fibrin enhances activity Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Cell/platelet-type plasminogen activator inhibitor from bovine aortic endothelial Homo sapiens
Placental-type plasminogen activator inhibitor
-
 Homo sapiens
Protease nexin-like plasminogen activator inhibitor
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
plasminogen + H2O Homo sapiens participation in the destruction of the follicle wall ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HMCB cell Bowes melanoma Homo sapiens
-
plasma in plasma no t-PA activity is found but, after acid treatment or euglobulin precipitation part of the t-PA becomes active, the t-PA activity in euglobulin fractions of normal individuals is highly variable from person to person Homo sapiens
-

Storage Stability

Storage Stability Organism
-80°C Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
plasminogen + H2O
-
 Homo sapiens plasmin + ?
-
 ?
plasminogen + H2O participation in the destruction of the follicle wall Homo sapiens ?
-
 ?