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Literature summary for 3.4.21.67 extracted from

  • Lee, C.S.; Hahm, J.K.; Hwang, B.J.; Park, K.C.; Ha, D.B.; Park, S.D.; Chung, C.H.
    Processing of Ada protein by two serine endoproteases Do and So from Escherichia coli (1990), FEBS Lett., 262, 310-312.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Ada protein + H2O Escherichia coli involved in endogenous cleavage of Ada protein (a DNA repair enzyme and a transcriptional activator of the expression of its own ada gene), which may play a role in down-regulating the adaptive response to alkylating agents ?
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Organism

Organism UniProt Comment Textmining
Escherichia coli
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ada protein + H2O a DNA repair enzyme and a transcriptional activator of the expression of its own ada gene, generation of a C-terminal 19000 MW polypeptide and further processing mainly to an 18000 MW fragment Escherichia coli 19000 MW polypeptide + 18000 MW fragment
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?
Ada protein + H2O involved in endogenous cleavage of Ada protein (a DNA repair enzyme and a transcriptional activator of the expression of its own ada gene), which may play a role in down-regulating the adaptive response to alkylating agents Escherichia coli ?
-
?