Literature summary for 3.4.21.66 extracted from

Fazelinia, H.; Cirino, P.C.; Maranas, C.D.
OptGraft: A computational procedure for transferring a binding site onto an existing protein scaffold (2009), Protein Sci., 18, 180-195.

Search for more literature for 3.4.21.66

Application

Application	Comment	Organism
biotechnology	computational procedure OptGraft for placing a novel binding pocket onto a protein structure so as its geometry is minimally perturbed. Transfer of a calcium-binding pocket from thermitase protein, PDB entry 1thm, into the first domain of rat CD2 protein, PDB entry 1hng results in new proteins that all exhibit high affinities for terbium and can selectively bind calcium over magnesium	Thermoactinomyces vulgaris

Protein Variants

Protein Variants	Comment	Organism
additional information	computational procedure OptGraft for placing a novel binding pocket onto a protein structure so as its geometry is minimally perturbed. Transfer of a calcium-binding pocket from thermitase protein, PDB entry 1thm, into the first domain of rat CD2 protein, PDB entry 1hng results in new proteins that all exhibit high affinities for terbium and can selectively bind calcium over magnesium	Thermoactinomyces vulgaris

Organism

Organism	UniProt	Comment	Textmining
Thermoactinomyces vulgaris	P04072	-	-

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Release 2023.1 (January 2023)