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Literature summary for 3.4.21.61 extracted from

  • Bang, S.; Chae, H.S.; Lee, C.; Choi, H.G.; Ryu, J.; Li, W.; Lee, H.; Jeong, G.S.; Chin, Y.W.; Shim, S.H.
    New aromatic compounds from the fruiting body of Sparassis crispa (Wulf.) and their inhibitory activities on proprotein convertase subtilisin/kexin type 9 mRNA expression (2017), J. Agric. Food Chem., 65, 6152-6157 .
    View publication on PubMed
Search for more literature for 3.4.21.61

Inhibitors

Inhibitors Comment Organism Structure
5alpha,6alpha-epoxy-(22E,24R)-ergosta-8(14),22-diene-3beta,7beta-diol isolated from fruiting bodies of Sparassis crispa Homo sapiens
adenosine
-
 Homo sapiens
Berberine
-
 Homo sapiens
hanabiratakelide A isolated from fruiting bodies of Sparassis crispa Homo sapiens
additional information identification of compounds by NMR spectroscopy Homo sapiens
sparoside A isolated from fruiting bodies of Sparassis crispa Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8NBP7
-
-

Synonyms

Synonyms Comment Organism
PCSK9
-
 Homo sapiens
proprotein convertase subtilisin/kexin type 9
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00718
-
 pH and temperature not specified in the publication Homo sapiens hanabiratakelide A
0.00804
-
 pH and temperature not specified in the publication Homo sapiens Berberine
0.00823
-
 pH and temperature not specified in the publication Homo sapiens 5alpha,6alpha-epoxy-(22E,24R)-ergosta-8(14),22-diene-3beta,7beta-diol
0.01846
-
 pH and temperature not specified in the publication Homo sapiens adenosine
0.0201
-
 pH and temperature not specified in the publication Homo sapiens sparoside A