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Literature summary for 3.4.21.61 extracted from

  • Billova, S.; Galanopoulou, A.S.; Seidah, N.G.; Qiu, X.; Kumar, U.
    Immunohistochemical expression and colocalization of somatostatin, carboxypeptidase-E and prohormone convertases 1 and 2 in rat brain (2007), Neuroscience, 147, 403-418.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm PC1 in striatum Rattus norvegicus 5737
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Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000
-
x * 87000, PC1, SDS-PAGE. x * 75000, proPC2, SDS-PAGE. x * 68000, mature PC2, SDS-PAGE Rattus norvegicus
75000
-
x * 87000, PC1, SDS-PAGE. x * 75000, proPC2, SDS-PAGE. x * 68000, mature PC2, SDS-PAGE Rattus norvegicus
87000
-
x * 87000, PC1, SDS-PAGE. x * 75000, proPC2, SDS-PAGE. x * 68000, mature PC2, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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adult male Sprague-Dawley rats
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Source Tissue

Source Tissue Comment Organism Textmining
brain
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Rattus norvegicus
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cerebral cortex mild expression of PC1 and moderate expression of PC2. PC1 and PC2 in cerebral cortex colocalizes in pyramidal and non-pyramidal neurons with carboxypeptidase-E and somatostatin Rattus norvegicus
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hippocampus weak expression of PC1 in CA1, CA2 and CA3 regions and nerve fibers. Moderate expression of PC2 in CA1, CA2 and CA3 regions and mild expression in nerve fibers. Colocalization of PC1 and PC2 with carboxypeptidase-E and somatostatin mostly selectively and preferentially in interneurons Rattus norvegicus
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additional information mild expression of PC1 and strong expression of PC2 in striatum. Colocalization of PC1 and PC2 with carboxypeptidase-E and somatostatin mostly selectively and preferentially in interneurons of the striatum Rattus norvegicus
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neuron
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Rattus norvegicus
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Subunits

Subunits Comment Organism
? x * 87000, PC1, SDS-PAGE. x * 75000, proPC2, SDS-PAGE. x * 68000, mature PC2, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
PC1
-
Rattus norvegicus
PC2
-
Rattus norvegicus
prohormone convertase 1
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Rattus norvegicus
prohormone convertase 2
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Rattus norvegicus