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Literature summary for 3.4.21.6 extracted from

  • Panteleev, M.A.; Ovanesov, M.V.; Kireev, D.A.; Shibeko, A.M.; Sinauridze, E.I.; Ananyeva, N.M.; Butylin, A.A.; Saenko, E.L.; Ataullakhanov, F.I.
    Spatial propagation and localization of blood coagulation are regulated by intrinsic and protein C pathways, respectively (2006), Biophys. J., 90, 1489-1500.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.6

Activating Compound

Activating Compound Comment Organism Structure
tissue factor TF
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 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
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 Homo sapiens 9986
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extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens blood clot elongation is regulated by factor Xa formation by intrinsic tenase, i.e. factor VIIa and tissue factor complex, coagulation factors from plasma bind to tissue factor TF-expressing cells, become activated, dissociate, and diffuse into plasma to form enzymatic complexes on the membranes of activated platelets, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification factor Xa formation is catalyzed by the intrinsic tenase, i.e. factor VIIa and tissue factor complex, via proteolytic cleavage, analysis of roles of extrinsic and intrinsic tenases in fX activation, and roles of extrinsic tenase and fXIa in fIX activation during clot formation in a reaction-diffusion system, computational simulations, overview Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood platelet coagulation factors from plasma bind to tissue factor TF-expressing cells, e.g. lung fibroblast, become activated, dissociate, and diffuse into plasma to form enzymatic complexes on the membranes of activated platelets, overview Homo sapiens
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plasma
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information blood clot elongation is regulated by factor Xa formation by intrinsic tenase, i.e. factor VIIa and tissue factor complex, coagulation factors from plasma bind to tissue factor TF-expressing cells, become activated, dissociate, and diffuse into plasma to form enzymatic complexes on the membranes of activated platelets, overview Homo sapiens ?
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 ?