Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | no activation of CA2+ responses by tissue factor TF or factor VIIa | Homo sapiens | |
additional information | no activation of CA2+ responses by tissue factor TF or factor VIIa | Bos taurus | |
Phospholipids | - |
Homo sapiens | |
Phospholipids | - |
Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
antithrombin | complete inhibition | Bos taurus | |
antithrombin | complete inhibition | Homo sapiens | |
DEGR-chloromethyl ketone | inactivation | Bos taurus | |
DEGR-chloromethyl ketone | inactivation | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
extracellular | - |
Bos taurus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | Ca2+-dependent binding of factor Xa to e.g. phospholipids | Homo sapiens | |
Ca2+ | Ca2+-dependent binding of factor Xa to e.g. phospholipids | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation, overview | ? | - |
? | |
additional information | Bos taurus | factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation, overview | ? | - |
? | |
protease-activated receptor 1 + H2O | Homo sapiens | PAR-1 activation mediates activation of phospholipase C in endothelial cells | activated protease-activated receptor 1 + ? | - |
? | |
protease-activated receptor 1 + H2O | Bos taurus | PAR-1 activation mediates activation of phospholipase C in endothelial cells | activated protease-activated receptor 1 + ? | - |
? | |
protease-activated receptor 2 + H2O | Homo sapiens | PAR-2 activation mediates activation of phospholipase C in endothelial cells | activated protease-activated receptor 2 + ? | - |
? | |
protease-activated receptor 2 + H2O | Bos taurus | PAR-2 activation mediates activation of phospholipase C in endothelial cells | activated protease-activated receptor 2 + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | the factor X is activated to factor Xa by Russell's viper venom | Homo sapiens |
proteolytic modification | the factor X is activated to factor Xa by Russell's viper venom | Bos taurus |
Purification (Comment) | Organism |
---|---|
native factor X from plasma | Homo sapiens |
native factor X from plasma | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
plasma | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
measurement of Ca2+ responses, oscillatory response pattern, overview | Homo sapiens |
additional information | - |
measurement of Ca2+ responses, oscillatory response pattern, overview | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation, overview | Homo sapiens | ? | - |
? | |
additional information | factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation, overview | Bos taurus | ? | - |
? | |
protease-activated receptor 1 + H2O | - |
Homo sapiens | activated protease-activated receptor 1 + ? | - |
? | |
protease-activated receptor 1 + H2O | - |
Bos taurus | activated protease-activated receptor 1 + ? | - |
? | |
protease-activated receptor 1 + H2O | PAR-1 activation mediates activation of phospholipase C in endothelial cells | Homo sapiens | activated protease-activated receptor 1 + ? | - |
? | |
protease-activated receptor 1 + H2O | PAR-1 activation mediates activation of phospholipase C in endothelial cells | Bos taurus | activated protease-activated receptor 1 + ? | - |
? | |
protease-activated receptor 2 + H2O | - |
Homo sapiens | activated protease-activated receptor 2 + ? | - |
? | |
protease-activated receptor 2 + H2O | - |
Bos taurus | activated protease-activated receptor 2 + ? | - |
? | |
protease-activated receptor 2 + H2O | PAR-2 activation mediates activation of phospholipase C in endothelial cells | Homo sapiens | activated protease-activated receptor 2 + ? | - |
? | |
protease-activated receptor 2 + H2O | PAR-2 activation mediates activation of phospholipase C in endothelial cells | Bos taurus | activated protease-activated receptor 2 + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
factor Xa | - |
Homo sapiens |
factor Xa | - |
Bos taurus |