Literature summary for 3.4.21.59 extracted from

Lee, J.W.; Park, J.H.; Park, D.I.; Park, J.H.; Kim, H.J.; Cho, Y.K.; Sohn, C.I.; Jeon, W.K.; Kim, B.I.
Subjects with diarrhea-predominant IBS have increased rectal permeability responsive to tryptase (2010), Digest. Dis. Sci., 55, 2922-2928.

Search for more literature for 3.4.21.59

Inhibitors

Inhibitors	Comment	Organism	Structure
Nafamostat	complete inhibition at 0.1 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
tosyl-glycine-L-proline-L-arginine-4-nitroanilide + H2O	-	Homo sapiens	tosyl-glycine-L-proline-L-arginine + 4-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
Mast cell tryptase	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	tryptase plays an important role in the control of human colonic mucosal permeability, and enhanced tryptase activity is responsible for the increased permeability of rectal mucosa in irritable bowel syndrome patients	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)