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Literature summary for 3.4.21.59 extracted from

  • Burgess, L.E.; Newhouse, B.J.; Ibrahim, P.; Rizzi, J.; Kashem, M.A.; Hartman, A.; Brandhuber, B.J.; Wright, C.D.; Thomson, D.S.; Vigers, G.P.; Koch, K.
    Potent selective nonpeptidic inhibitors of human lung tryptase (1999), Proc. Natl. Acad. Sci. USA, 96, 8348-8352.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine potent and selective inhibitor of tryptase will be an essential tool to determine the role of tryptase in inflammation and other processes, tryptase plays a role in asthma and other allergic and inflammatory skin diseases like psoriasis and atopic dermatitis Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
benzamidine
-
Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
secretory granule
-
Homo sapiens 30141
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
human
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining

Subunits

Subunits Comment Organism
homotetramer
-
Homo sapiens

Synonyms

Synonyms Comment Organism
human lung tryptase
-
Homo sapiens