General Stability | Organism |
---|---|
ATP stabilizes | Escherichia coli |
glycerol stabilizes | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Escherichia coli | |
ADP | - |
Rattus norvegicus | |
diisopropyl fluorophosphate | E. coli | Escherichia coli | |
diisopropyl fluorophosphate | - |
Rattus norvegicus | |
N-ethylmaleimide | - |
Escherichia coli | |
N-ethylmaleimide | - |
Rattus norvegicus | |
PMSF | - |
Escherichia coli | |
PMSF | - |
Rattus norvegicus | |
vanadate | - |
Escherichia coli | |
vanadate | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | requirement | Escherichia coli | |
Mg2+ | requirement | Rattus norvegicus | |
Mg2+ | requirement | Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
87000 | - |
4 * 87000, | Escherichia coli |
360000 | - |
E. coli | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | ATP-dependent serine protease | ? | - |
? | |
additional information | Rattus norvegicus | ATP-dependent serine protease | ? | - |
? | |
Proteins with highly abnormal conformation + H2O | Escherichia coli | catalyzes inital step in the degradation of proteins with abnormal conformation as may result from nonsense or missense mutations, biosynthetic errors or intracellular denaturation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Escherichia coli | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
hydrolysis of proteins in presence of ATP | hydrolysis of proteins in presence of ATP, mechanism | Escherichia coli | |
hydrolysis of proteins in presence of ATP | hydrolysis of proteins in presence of ATP, mechanism | Rattus norvegicus | |
hydrolysis of proteins in presence of ATP | hydrolysis of proteins in presence of ATP, mechanism | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Bos taurus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
casein + H2O | - |
Escherichia coli | hydrolyzed casein | - |
? | |
casein + H2O | - |
Rattus norvegicus | hydrolyzed casein | - |
? | |
casein + H2O | - |
Bos taurus | hydrolyzed casein | - |
? | |
Denatured albumin + H2O | - |
Escherichia coli | ? | - |
? | |
Globin + H2O | - |
Escherichia coli | ? | - |
? | |
Glutaryl-Ala-Ala-Phe-methoxynaphthylamide + H2O | - |
Escherichia coli | Glutaryl-Ala-Ala-Phe + methoxynaphthylamine | - |
? | |
additional information | ATP-dependent serine protease | Escherichia coli | ? | - |
? | |
additional information | ATP-dependent serine protease | Rattus norvegicus | ? | - |
? | |
Proteins with highly abnormal conformation + H2O | catalyzes inital step in the degradation of proteins with abnormal conformation as may result from nonsense or missense mutations, biosynthetic errors or intracellular denaturation | Escherichia coli | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 87000, | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
Escherichia coli | Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | requirement | Escherichia coli | |
ATP | two ATP molecules are hydrolyzed for each peptide bond cleaved in proteins | Escherichia coli | |
ATP | ATP-dependent protease | Escherichia coli | |
ATP | ATP-dependent protease | Rattus norvegicus | |
ATP | ATP-dependent protease | Bos taurus |