Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
x * 30000, about, SDS-PAGE | Pseudomonas aeruginosa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Pseudomonas aeruginosa | the enzyme inhibits four host cell surfactant-associated proteins designated SP-A, SP-B, SP-C, and SP-D, degradation of SPs by protease IV inhibits their ability to enhance bacterial association with alveolar macrophages, overview | ? | - |
? | |
additional information | Pseudomonas aeruginosa PA103-29 | the enzyme inhibits four host cell surfactant-associated proteins designated SP-A, SP-B, SP-C, and SP-D, degradation of SPs by protease IV inhibits their ability to enhance bacterial association with alveolar macrophages, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Pseudomonas aeruginosa PA103-29 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme from strain PA103-29 by ion exchange chromatography and gel filtration, or from strain PAO1-B1 supernatants by ultrafiltration, anion exchange and hydrophobic interaction chromatography | Pseudomonas aeruginosa |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
pathogen-host surface activity analysis, overview | Pseudomonas aeruginosa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme inhibits four host cell surfactant-associated proteins designated SP-A, SP-B, SP-C, and SP-D, degradation of SPs by protease IV inhibits their ability to enhance bacterial association with alveolar macrophages, overview | Pseudomonas aeruginosa | ? | - |
? | |
additional information | the enzyme inhibits four host cell surfactant-associated proteins designated SP-A, SP-B, SP-C, and SP-D, degradation of SPs by protease IV inhibits their ability to enhance bacterial association with alveolar macrophages, overview | Pseudomonas aeruginosa PA103-29 | ? | - |
? | |
tosyl-Gly-Pro-Lys-4-nitroanilide + H2O | a chromogenic substrate | Pseudomonas aeruginosa | tosyl-Gly-Pro-Lys + 4-nitroaniline | - |
? | |
tosyl-Gly-Pro-Lys-4-nitroanilide + H2O | a chromogenic substrate | Pseudomonas aeruginosa PA103-29 | tosyl-Gly-Pro-Lys + 4-nitroaniline | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 30000, about, SDS-PAGE | Pseudomonas aeruginosa |
Synonyms | Comment | Organism |
---|---|---|
protease IV | - |
Pseudomonas aeruginosa |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | 37 | assay at | Pseudomonas aeruginosa |