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Literature summary for 3.4.21.5 extracted from
- Crystal structure of thrombin bound to the uncleaved extracellular fragment of PAR1 (2010), J. Biol. Chem., 285, 15393-15398.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| thrombin mutant S195A in complex with a 30-residue long uncleaved extracellular fragment of protease-activated receptor 1, hanging drop vapor diffusion method, using 0.2 M potassium/sodium tartrate, 20%,(w/v) PEG 3350, at 22°C | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| S195A | inactive | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha-thrombin | - |
Homo sapiens |
| fibrinogenase | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | thrombin activates protease-activated receptors 1, 3, and 4, but not 2 | Homo sapiens |
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Release 2023.1 (January 2023)
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