Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dabigatran | BIBR 953, potent competitive and reversible inhibitor of thrombin, inhibiting both thrombin activity and generation, dabigatran displays highly selective, rapid, and reversible binding to thrombin8 and potently inhibits platelet aggregation with a concentration that produces 50% inhibition similar to the Ki of thrombin | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
fibrinogen + H2O | Homo sapiens | - |
fibrin + fibrinopeptide A + fibrinopeptide B | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
fibrinogen + H2O | - |
Homo sapiens | fibrin + fibrinopeptide A + fibrinopeptide B | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0000045 | - |
dabigatran | - |
Homo sapiens |