Literature summary for 3.4.21.5 extracted from

Johnson, D.J.; Adams, T.E.; Li, W.; Huntington, J.A.
Crystal structure of wild-type human thrombin in the Na+-free state (2005), Biochem. J., 392, 21-28.

Activating Compound

Activating Compound	Comment	Organism	Structure
Na+	in Na+-free form, enzyme is in an equilibrium between an inert species and an active form, where the addition of Na+ populates the active state	Homo sapiens

Crystallization (Comment)	Organism
Na+-free form, Na+-binding site is in a highly ordered position slightly removed from that seen in the Na+-bound state	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	P00734	-	-

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Release 2023.1 (January 2023)