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Literature summary for 3.4.21.47 extracted from

  • Wu, J.; Wu, Y.Q.; Ricklin, D.; Janssen, B.J.; Lambris, J.D.; Gros, P.
    Structure of complement fragment C3b-factor H and implications for host protection by complement regulators (2009), Nat. Immunol., 10, 728-733.
    View publication on PubMedView publication on EuropePMC
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Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with factor H, hanging drop vapor diffusion method, using 7.0% (w/v) PEG 3350, 70 mM ammonium acetate, pH 7.1, at 18°C Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
staphylococcal complement inhibitor
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C3 + H2O
-
 Homo sapiens complement component C3a + complement component C3b
-
 ?

Synonyms

Synonyms Comment Organism
alternative pathway C3 convertase complex
-
 Homo sapiens
C3bBb
-
 Homo sapiens