Crystallization (Comment) | Organism |
---|---|
C3 convertase formed by C3b and the protease fragment Bb in complex with staphylococcal complement inhibitor, hanging drop vapor diffusion method, using 75 mM sodium/potassium tartrate, 8.0% (w/v) PEG 3350, 50 mM Bis-Tris propane, pH 6.5 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
staphylococcal complement inhibitor | from Staphylococcus aureus, binds and blocks active convertases in solution and induced dimerization of C3bBb | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
magnetic cobalt beads chromatography and analytical ultracentrifugation | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
complement component C3 + H2O | - |
Homo sapiens | complement component C3a + complement component C3b | - |
? |
Synonyms | Comment | Organism |
---|---|---|
alternative complement pathway C3 convertase | - |
Homo sapiens |
C3bBb | - |
Homo sapiens |