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Literature summary for 3.4.21.47 extracted from
- Anti-factor B autoantibody in dense deposit disease (2010), Mol. Immunol., 47, 1476-1483.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | the anti-factor B autoantibody binds to factor B and to the alternative pathway C3 convertase and alters the kinetics of complement activation and regulation, the anti-factor B autoantibody does not influence the assembly of the C3 convertase | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| complement component C3 + H2O | - |
Homo sapiens | complement component C3a + complement component C3b | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alternative pathway C3 convertase | - |
Homo sapiens |
| C3bBb convertase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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