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Literature summary for 3.4.21.47 extracted from

  • Hourcade, D.E.
    The role of properdin in the assembly of the alternative pathway C3 convertases of complement (2006), J. Biol. Chem., 281, 2128-2132.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
properdin surface plasmon resonance assays, properdin promotes the association of C3b with factor B and provides a focal point for the assembly of enzyme on a surface. Properdin can use its unoccupied C3b-binding sites as receptors and form a lattice of properdin-C3b, -C3bB and C3bBb complexes leading to in situ assembly of enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
comercial preparation
-