Literature summary for 3.4.21.47 extracted from

Koelln, J.; Bredehorst, R.; Spillner, E.
Engineering of human complement component C3 for catalytic inhibition of complement (2005), Immunol. Lett., 98, 49-56.

Search for more literature for 3.4.21.47

Application

Application	Comment	Organism
medicine	intervention in complement-mediated pathologies by modulation of enzyme half-life through replacement of enzyme compoment C3 by the corresponding sequences of cobra venom factor from Naja kaouthia	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	replacement of C-terminal sequences of enzyme compoment C3 by the corresponding sequences of cobra venom factor from Naja kaouthia. Major role of NTR/C345C motiv in regulation of enzyme half-life	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
200000	-	x * 200000, enzyme component C3, SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Subunits

Subunits	Comment	Organism
?	x * 200000, enzyme component C3, SDS-PAGE	Homo sapiens

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Release 2023.1 (January 2023)