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Literature summary for 3.4.21.45 extracted from

  • Nagasawa, S.; Ichihara, C.; Stroud, R.M.
    Cleavage of C4b by C3b inactivator: production of a nicked form of C4b, C4b', as an intermediate cleavage product of C4b by C3b inactivator (1980), J. Immunol., 125, 578-582.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
C4bC3bINACo cofactor in cleavage of C4b Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C4b + H2O a nicked form of complement component C4b, complement component C4b', consisting of four disulfide-linked polypeptide chains, is formed as an intermediate product before cleavage of complement component C4b into complement component C4c and complement component C4d Homo sapiens complement component C4c + C4d
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