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Literature summary for 3.4.21.45 extracted from
- Support for the involvement of complement factor I in age-related macular degeneration (2010), Eur. J. Hum. Genet., 18, 15-16.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | case-control study of factor I gene involving 190 DNA samples from macular degeneration patients and 179 control samples genotypes six single nucleotide polymorphisms. Four single nucleotide polymorphisms are nominally significant in this initial analysis, and no single single nucleotide polymorphism maintains marginal significance after conservative Bonferroni correction for multiple testing. These four single nucleotide polymorphisms have very similar minor allele frequencies and are likely to be genetically hitchhiking with one another. Data implicate genomic variation in the region of the complement factor I gene with age-related macular disease susceptibility | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
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Release 2023.1 (January 2023)
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