Application | Comment | Organism |
---|---|---|
medicine | studies on inflammatory kidney disease membranoproliferative glomerulonephritis type II (MPGN2) | Mus musculus |
Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli, generation of mice strains deficient of complement factor I | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
88000 | - |
SDS-PAGE, nonreducing conditions, detection of murine complement factor I by using a crossreactive polyclonal goat antibody against human complement factor I | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
complement component C3b + H2O | Mus musculus | - |
complement component C3c + ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q61129 | - |
- |
Purification (Comment) | Organism |
---|---|
gel filtration | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | renal transplantation studies of mice included | Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
complement component C3 level measured in plasma, glomerular complement component C3 staining and complement profile in mice with deficiency of complement factor I indicated | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
complement component C3b + H2O | - |
Mus musculus | complement component C3c + ? | - |
? | |
complement component C3b + H2O | studies on membranoproliferative glomerulonephritis, potential relation to complement factor I analyzed | Mus musculus | complement component C3c + ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | - |
Mus musculus |