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Literature summary for 3.4.21.42 extracted from

  • Kerr, F.K.; OBrien, G.; Quinsey, N.S.; Whisstock, J.C.; Boyd, S.; de la Banda, M.G.; Kaiserman, D.; Matthews, A.Y.; Bird, P.I.; Pike, R.N.
    Elucidation of the substrate specificity of the C1s protease of the classical complement pathway (2005), J. Biol. Chem., 280, 39510-39514.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminobenzoyl-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Ile-Lys(dinitrophenyl)-NH2 + H2O
-
Homo sapiens 2-aminobenzoyl-Gly-Leu-Gln-Arg + Ala-Leu-Glu-Ile-Lys(dinitrophenyl)-NH2
-
?
2-aminobenzoyl-Gly-Tyr-Leu-Gly-Arg-Ser-Tyr-Lys-Val-Gly-Lys(dinitrophenyl)-Asp-OH + H2O substrate obtained from phage display analysis, 4.7fold higher procession than the natural C1s protease substrate (SLGRKIQI) Homo sapiens 2-aminobenzoyl-Gly-Tyr-Leu-Gly-Arg + Ser-Tyr-Lys-Val-Gly-Lys(dinitrophenyl)-Asp-OH + H2O
-
?
2-aminobenzoyl-Ser-Leu-Gly-Arg-Lys-Ile-Gln-Ile-Lys(dinitrophenyl)-NH2 + H2O
-
Homo sapiens 2-aminobenzoyl-Ser-Leu-Gly-Arg + Lys-Ile-Gln-Ile-Lys(dinitrophenyl)-NH2
-
?
2-aminobenzoyl-Ser-Val-Ala-Arg-Thr-Leu-Leu-Lys(dinitrophenyl)-NH2 + H2O
-
Homo sapiens 2-aminobenzoyl-Ser-Val-Ala-Arg + Thr-Leu-Leu-Lys(dinitrophenyl)-NH2 + H2O
-
?

Synonyms

Synonyms Comment Organism
C1s protease
-
Homo sapiens
complement protease C1s
-
Homo sapiens