Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.42 extracted from

  • Harmat, V.; Gal, P.; Kardos, J.; Szilagyi, K.; Ambrus, G.; Vegh, B.; Naray-Szabo, G.; Zavodszky, P.
    The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions (2004), J. Mol. Biol., 342, 1533-1546.
    View publication on PubMed
Search for more literature for 3.4.21.42

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL-21 DE3 pLysS Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information only the fragment bearing the serine protease (SP) and the complement control protein (CCP) module 2 of MASP-2 were expressed and crystallized Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C2 + H2O Homo sapiens
-
 complement component C2a + complement component C2b
-
 ?
complement component C4 + H2O Homo sapiens
-
 complement component C4a + complement component C4b
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C2 + H2O
-
 Homo sapiens complement component C2a + complement component C2b
-
 ?
complement component C4 + H2O
-
 Homo sapiens complement component C4a + complement component C4b
-
 ?

Synonyms

Synonyms Comment Organism
MASP-2
-
 Homo sapiens
MBL-associated serine protease-2
-
 Homo sapiens