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BRENDA support

Literature summary for 3.4.21.41 extracted from

  • Goesswein, T.; Kocot, A.; Emmert, G.; Kreuz, W.; Martinez-Saguer, I.; Aygoeren-Puersuen, E.; Rusicke, E.; Bork, K.; Oldenburg, J.; Mueller, C.R.
    Mutational spectrum of the C1INH (SERPING1) gene in patients with hereditary angioedema (2008), Cytogenet. Genome Res., 121, 181-188.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
C1INH sole inhibitor of the activated proteases C1r and C1s. Hereditary angioedema results from functional deficiency of the C1 inhibitor (C1INH) protein, which plays a key role in the classical pathway of complement activation Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
C1r
-
Homo sapiens