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Literature summary for 3.4.21.4 extracted from

  • Li, J.; Wu, J.; Wang, Y.; Xu, X.; Liu, T.; Lai, R.; Zhu, H.
    A small trypsin inhibitor from the frog of Odorrana grahami (2008), Biochimie, 90, 1356-1361.
    View publication on PubMed
Search for more literature for 3.4.21.4

Inhibitors

Inhibitors Comment Organism Structure
AVNIPFKVHFRCKAAFC a small trypsin inhibitor from the skin secretion of the frog Odorrana grahami, only inhibits the hydrolysis activity of trypsin on synthetic chromogenic substrate Bos taurus
LKGCWTKSIPPKPCFGK
-
 Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pancreas
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ANVIPFKVHFRAAFC + H2O
-
 Bos taurus ANVIPFK + VHFR + AAFC
-
 ?
D-Phe-Pip-Arg 4-nitroanilide + H2O
-
 Bos taurus D-Phe-Pip-Arg + 4-nitroaniline
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0004
-
 AVNIPFKVHFRCKAAFC in 50 mM Tris-HCl, pH 7.8, at 37°C Bos taurus