Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3,4-dichloroisocoumarin | - |
Mus musculus | |
Alpha1-proteinase inhibitor | - |
Mus musculus | |
diisopropyl fluorophosphate | - |
Mus musculus | |
phenylmethylsulfonyl fluoride | - |
Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.663 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1C | Mus musculus | |
0.832 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1E | Mus musculus | |
0.922 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1A | Mus musculus | |
0.936 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1D | Mus musculus | |
0.991 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1B | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
30000 | - |
1 * 30000, enzyme form MMCP-1D and MMCP-1E, SDS-PAGE | Mus musculus |
31000 | - |
1 * 31000, enzyme form MMCP-1B and MMCP-1C, SDS-PAGE | Mus musculus |
32000 | - |
1 * 32000 + 1 * 33000, enzyme form MMCP-1A, SDS-PAGE | Mus musculus |
33000 | - |
1 * 32000 + 1 * 33000, enzyme form MMCP-1A, SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
5 enzyme forms: MMCP-1A to MMCP-1E | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | 5 variant glycoforms, differences in the electrophoretic mobility between the variant forms of MMCP-1 are probably a result of variable glycosylation | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mast cell | - |
Mus musculus | - |
small intestine | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoyl-Arg-4-nitroanilide + H2O | no activity with enzyme forms 1D and 1E | Mus musculus | benzoyl-Arg + 4-nitroaniline | - |
? | |
benzoyl-L-Tyr-4-nitroanilide + H2O | activity with enzyme form 1A, no activity with enzyme form 1B, 1C, 1D, 1E | Mus musculus | benzoyl-L-Tyr + 4-nitroaniline | - |
? | |
benzyloxycarbonyl-Ala-4-nitrophenyl ester + H2O | - |
Mus musculus | benzyloxycarbonyl-Ala + 4-nitrophenyl | - |
? | |
benzyloxycarbonyl-Arg-4-nitrophenyl ester + H2O | no activity with enzyme form 1B, 1C and 1E | Mus musculus | benzyloxycarbonyl-Arg + 4-nitrophenol | - |
? | |
benzyloxycarbonyl-D-Ala-4-nitrophenyl ester + H2O | - |
Mus musculus | benzyloxycarbonyl + D-Ala-4-nitrophenol | - |
? | |
benzyloxycarbonyl-Phe-4-nitrophenyl ester + H2O | - |
Mus musculus | benzyloxycarbonyl-Phe + 4-nitrophenol | - |
? | |
benzyloxycarbonyl-Trp-4-nitrophenyl ester + H2O | - |
Mus musculus | benzyloxycarbonyl-Trp + 4-nitrophenol | - |
? | |
benzyloxycarbonyl-Tyr-4-nitrophenyl ester + H2O | no activity with enzyme form 1C and 1E | Mus musculus | benzyloxycarbonyl-Tyr-4-nitrophenyl ester | - |
? | |
succinyl-Phe-4-nitroanilide + H2O | no activity with enzyme form 1C and 1D | Mus musculus | succinyl-Phe + 4-nitroaniline | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 1 * 32000 + 1 * 33000, enzyme form MMCP-1A, SDS-PAGE | Mus musculus |
monomer | 1 * 30000, enzyme form MMCP-1D and MMCP-1E, SDS-PAGE | Mus musculus |
monomer | 1 * 31000, enzyme form MMCP-1B and MMCP-1C, SDS-PAGE | Mus musculus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.25 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1E | Mus musculus | |
1.66 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1B | Mus musculus | |
2.33 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1A | Mus musculus | |
2.54 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1D | Mus musculus | |
2.84 | - |
succinyl-Ala-Ala-Pro-Phe-4-nitroanilide | enzyme form 1C | Mus musculus |