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Literature summary for 3.4.21.39 extracted from

  • Gendrin, C.; Shubin, N.J.; Boldenow, E.; Merillat, S.; Clauson, M.; Power, D.; Doran, K.S.; Abrink, M.; Pejler, G.; Rajagopal, L.; Piliponsky, A.M.
    Mast cell chymase decreases the severity of group B Streptococcus infections (2018), J. Allergy Clin. Immunol., 142, 120-129.e6 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.39

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fibronectin + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell
-
 Mus musculus
-
peritoneal cell-derived mast cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibronectin + H2O
-
 Mus musculus ?
-
 ?
methoxysuccinyl-Arg-Pro-Tyr-4-nitroanilide + H2O
-
 Mus musculus methoxysuccinyl-Arg-Pro-Tyr + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
mast cell chymase
-
 Mus musculus
mast cell protease 4
-
 Mus musculus
MCPT4
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus mast cells release the enzyme upon GBS exposure up

General Information

General Information Comment Organism
physiological function the enzyme decreases the severity of group B Streptococcus infections Mus musculus