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Literature summary for 3.4.21.39 extracted from

  • Houde, M.; Jamain, M.D.; Labonte, J.; Desbiens, L.; Pejler, G.; Gurish, M.; Takai, S.; DOrleans-Juste, P.
    Pivotal role of mouse mast cell protease 4 in the conversion and pressor properties of Big-endothelin-1 (2013), J. Pharmacol. Exp. Ther., 346, 31-37.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.39

Inhibitors

Inhibitors Comment Organism Structure
TY-51469 specific chymase inhibitor, i.e. 2-[4-(5-fluoro-3-methylbenzo[b]thiophen-2-yl)sulfonamido-3-methanesulfonylphenyl]thiazole-4-carboxylic acid Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
angiotensin I + H2O Mus musculus
-
 angiotensin II + His-Leu
-
 ?
Big-endothelin-1 + H2O Mus musculus
-
 endothelin-1 (1-31) + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P21812
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Mus musculus
-
mast cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
angiotensin I + H2O
-
 Mus musculus angiotensin II + His-Leu
-
 ?
Big-endothelin-1 + H2O
-
 Mus musculus endothelin-1 (1-31) + ?
-
 ?
methoxysuccinyl-Arg-Ala-Tyr-4-nitroanilide + H2O
-
 Mus musculus methoxysuccinyl-Arg-Ala-Tyr + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
mast cell protease 4
-
 Mus musculus
MCP-4
-
 Mus musculus