Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
tissue necrosis factor + H2O | Mus musculus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P21812 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mast cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
tissue necrosis factor + H2O | - |
Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
mast cell protease 4 | - |
Mus musculus |
MCP-4 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme-deficient mice exhibit higher numbers of peritoneal neutrophils and increased acute kidney injury after cecal ligation and puncture, and also have significantly higher mortality after this procedure | Mus musculus |
physiological function | MCP-4 can enhance survival after cecal ligation and puncture at least in part by limiting detrimental effects of tissue necrosis factor | Mus musculus |