Literature summary for 3.4.21.39 extracted from

Belkowski, S.M.; Boot, J.D.; Mascelli, M.A.; Diamant, Z.; de Garavilla, L.; Hertzog, B.; Polkovitch, D.; Towers, M.; Batheja, A.; D�Andrea, M.R.
Cleaved secretory leucocyte protease inhibitor as a biomarker of chymase activity in allergic airway disease (2009), Clin. Exp. Allergy, 39, 1179-1186.

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Inhibitors

Inhibitors	Comment	Organism	Structure
secretory leucocyte protease inhibitor	-	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
nasal lavage fluid	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
secretory leucocyte protease inhibitor + H2O	cleaved secretory leucocyte protease inhibitor is a biomarker of chymase activity	Homo sapiens	?	-	?

Expression

Organism	Comment	Expression
Homo sapiens	there is a significant increase in the nasal lavage chymase levels in the allergen-challenged individuals as compared with placebo-exposed individuals	up

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Release 2023.1 (January 2023)