Literature summary for 3.4.21.39 extracted from

Inoue, N.; Muramatsu, M.; Jin, D.; Takai, S.; Hayashi, T.; Katayama, H.; Kitaura, Y.; Tamai, H.; Miyazaki, M.
Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice (2008), Atherosclerosis, 204, 359-364.

Search for more literature for 3.4.21.39

Application

Application	Comment	Organism
medicine	chymase is involved in angiotnesin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice	Mus musculus

Inhibitors

Inhibitors	Comment	Organism	Structure
NK-3201	-	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
angiotensin I + H2O	Mus musculus	-	angiotensin II + His-Leu	-	?
promatrix metalloproteinase-9 + H2O	Mus musculus	-	matrix metalloproteinase-9	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
angiotensin I + H2O	-	Mus musculus	angiotensin II + His-Leu	-	?
methoxysuccinyl-Arg-Ala-Tyr-4-nitroanilide + H2O	-	Mus musculus	methoxysuccinyl-Arg-Ala-Tyr + 4-nitroaniline	-	?
promatrix metalloproteinase-9 + H2O	-	Mus musculus	matrix metalloproteinase-9	-	?

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Release 2023.1 (January 2023)