Literature summary for 3.4.21.38 extracted from

Yamamoto, T.; Shibuya, Y.; Nishino, N.; Okabe, H.; Kambara, T.
Activation of human Hageman factor by Pseudomonas aeruginosa elastase in the presence or absence of negatively charged substance in vitro (1990), Biochim. Biophys. Acta, 1038, 231-239.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	participation of the Hageman factor-dependent system in the inflammatory response to pseudomonal infections, due to the initiation of the system by bacterial elastase	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
proteolytic modification	the zymogen is activated by Pseudomonas aeruginosa elastase. In this activation factor XII is cleaved in a limited fashion, liberating fragments with apparent molecular masses of 40000 Da and 30000 Da	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	participation of the Hageman factor-dependent system in the inflammatory response to pseudomonal infections, due to the initiation of the system by bacterial elastase	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)