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Literature summary for 3.4.21.38 extracted from
- Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates (2013), J. Thromb. Haemost., 11, 1341-1352.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| High molecular weight kininogen | - |
Homo sapiens | |
| long-chain polyphosphate | - |
Homo sapiens | |
| plasma prekallikrein | - |
Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| corn trypsin inhibitor | - |
Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| factor XI + H2O | Homo sapiens | - |
factor XIa + ? | - |
? |  |
| prekallikrein + H2O | Homo sapiens | - |
kallikrein + kallikrein prepeptide | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P00748 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| factor XI + H2O | - |
Homo sapiens | factor XIa + ? | - |
? | |
| prekallikrein + H2O | - |
Homo sapiens | kallikrein + kallikrein prepeptide | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| factor XII | - |
Homo sapiens |
| FXII | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates | Homo sapiens |
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