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Literature summary for 3.4.21.37 extracted from

  • Feng, L.; Liu, X.; Zhu, W.; Guo, F.; Wu, Y.; Wang, R.; Chen, K.; Huang, C.; Li, Y.
    Inhibition of human neutrophil elastase by pentacyclic triterpenes (2013), PLoS ONE, 8, e82794.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.37

Inhibitors

Inhibitors Comment Organism Structure
astragaloside IV
-
 Homo sapiens
betulinic acid
-
 Homo sapiens
cucurbitacin B
-
 Homo sapiens
ginsenoside Re
-
 Homo sapiens
glycyrrhetinic acid
-
 Homo sapiens
glycyrrhizin
-
 Homo sapiens
lupeol
-
 Homo sapiens
oleanolic acid
-
 Homo sapiens
piefeltarraenin IA
-
 Homo sapiens
shionone
-
 Homo sapiens
sivelestat sodium hydrate ONO-5046, selective inhibitor Homo sapiens
toosendanin
-
 Homo sapiens
ursolic acid highest inhibitory potency Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 x * 30000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Elastin + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Elastin + H2O
-
 Homo sapiens ?
-
 ?
methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O
-
 Homo sapiens methoxysuccinyl-Ala-Ala-Pro-Val + 4-nitroaniline
-
 ?

Subunits

Subunits Comment Organism
? x * 30000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
HNE
-
 Homo sapiens
neutrophil elastase
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00551
-
 pH and temperature not specified in the publication Homo sapiens ursolic acid