Literature summary for 3.4.21.37 extracted from

Hayashi, M.; Oya, A.; Miyake, H.; Nakai, A.; Takeshita, T.
Effect of urinary trypsin inhibitor on preterm labor with high granulocyte elastase concentration in cervical secretions (2010), J. Nippon Med. Sch., 77, 80-85.

Search for more literature for 3.4.21.37

Application

Application	Comment	Organism
drug development	suppression of the enzyme reduces the risk of preterm delivery and improved neonatal outcomes and is therefore a target for inhibitor development	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	patients of preterm show increased levels of granulocyte elastase in cervical secretions from 16 to 33 weeks gestation	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
granulocyte elastase	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	urinary trypsin inhibitor, UTI, a member of the inter-alpha trypsin inhibitor family, suppresses neutrophile leastase and granulocyte elastase in vivo	down

General Information

General Information	Comment	Organism
malfunction	granulocyte elastase is involved in preterm and is increased in cervical secretion before gestation, urinary trypsin inhibitor reduces the risk of preterm delivery and improved neonatal outcomes	Homo sapiens

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Release 2023.1 (January 2023)