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Literature summary for 3.4.21.37 extracted from

  • Ujiie, Y.; Shimada, A.; Komatsu, K.; Gomi, K.; Oida, S.; Arai, T.; Fukae, M.
    Degradation of noncollagenous components by neutrophil elastase reduces the mechanical strength of rat periodontal ligament (2008), J. Periodont. Res., 43, 22-31.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
sivelestat also known as Elaspol, a synthetic inhibitor of neutrophil elastase with high specificity Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
oxytalan fibre + H2O Homo sapiens the elastase degrades the interfibrillar substances in the periodontal ligament and exposed individual collagen fibrils but not the collagen fibers of the transverse sections of rat mandibular first molars ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-methoxysuccinyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O
-
 Homo sapiens N-methoxysuccinyl-Ala-Ala-Pro-Val + 4-nitroaniline
-
 ?
oxytalan fibre + H2O the elastase degrades the interfibrillar substances in the periodontal ligament and exposed individual collagen fibrils but not the collagen fibers of the transverse sections of rat mandibular first molars Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
neutrophil elastase
-
 Homo sapiens