Inhibitors | Comment | Organism | Structure |
---|---|---|---|
EPI-hNE-4 | highly specific, potent inhibitor, protective effect in repeated injury animal model | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Elastin + H2O | Rattus norvegicus | involved in lung defense against bacterial infection, due to the ability of the enzyme to cleave cell surface proteins, body cells might also be damaged, could participate in neutrophil migration | ? | protein cleaved at at least one location | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Sprague-Dawley rats, repeated lung injury model | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leukocyte | - |
Rattus norvegicus | - |
lung | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-Ala-Ala-Pro-Val-4-nitroanilide + H2O | - |
Rattus norvegicus | acetyl-Ala-Ala-Pro-Val + 4-nitroaniline | - |
? | |
Elastin + H2O | - |
Rattus norvegicus | ? | - |
? | |
Elastin + H2O | involved in lung defense against bacterial infection, due to the ability of the enzyme to cleave cell surface proteins, body cells might also be damaged, could participate in neutrophil migration | Rattus norvegicus | ? | protein cleaved at at least one location | ? |