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Literature summary for 3.4.21.37 extracted from
- Kinetics of proteolysis of hog gastric mucin by human neutrophil elastase and by Pseudomonas aeruginosa elastase (1988), Infect. Immun., 56, 703-704.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | Homo sapiens | involved in lung defense against bacterial infection, due to the ability of the enzyme to cleave cell surface proteins, body cells might also be damaged | ? | protein cleaved at at least one location | ? |  |
| mucin + H2O | Homo sapiens | proteolysis of mucin is suggested to be involved in cell damaging processes during chronic infection and inflammation of the respiratory tract | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | lung secretions from lung of chronically infected patients suffering from bronchitis or cystic fibrosis | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Elastin + H2O | - |
Homo sapiens | ? | - |
? | |
| Elastin + H2O | involved in lung defense against bacterial infection, due to the ability of the enzyme to cleave cell surface proteins, body cells might also be damaged | Homo sapiens | ? | protein cleaved at at least one location | ? | |
| mucin + H2O | proteolysis of mucin is suggested to be involved in cell damaging processes during chronic infection and inflammation of the respiratory tract | Homo sapiens | ? | - |
? | |
| mucin + H2O | hog gastric mucin | Homo sapiens | ? | - |
? | |
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