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Literature summary for 3.4.21.37 extracted from

  • Melby, K.; Toews, G.B.; Pierce, A.K.
    Pulmonary elastase activity in response to Streptococcus pneumoniae and Pseudomonas aeruginosa (1985), Am. Rev. Respir. Dis., 131, 559-563.
    View publication on PubMed
Search for more literature for 3.4.21.37

Inhibitors

Inhibitors Comment Organism Structure
diisopropyl fluorophosphates almost complete inhibition Cricetulus griseus
EDTA slight inhibition Cricetulus griseus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Elastin + H2O Cricetulus griseus involved in lung defense against bacterial infection, due to the ability of the enzyme to cleave cell surface proteins, body cells might also be damaged ? protein cleaved at at least one location ?

Organism

Organism UniProt Comment Textmining
Cricetulus griseus
-
 male Syrian golden hamsters infected with different strains of Pseudomonas aeruginosa
-

Source Tissue

Source Tissue Comment Organism Textmining
granulocyte
-
 Cricetulus griseus
-
lung bronchoalveolar lavage fluid Cricetulus griseus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Elastin + H2O
-
 Cricetulus griseus ?
-
 ?
Elastin + H2O involved in lung defense against bacterial infection, due to the ability of the enzyme to cleave cell surface proteins, body cells might also be damaged Cricetulus griseus ? protein cleaved at at least one location ?
succinyl-Ala-Ala-Ala-p-nitroanilide + H2O
-
 Cricetulus griseus succinyl-Ala-Ala-Ala + p-nitroaniline
-
 ?