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Literature summary for 3.4.21.35 extracted from

  • Zhang, Q.; Ding, H.; Yan, J.; Wang, W.; Ma, A.; Zhu, Z.; Cianflone, K.; Hu, F.B.; Hui, R.; Wang, D.W.
    Plasma tissue kallikrein level is negatively associated with incident and recurrent stroke: a multicenter case-control study in China (2011), Ann. Neurol., 70, 265-273.
    View publication on PubMed
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Application

Application Comment Organism
medicine plasma tissue kallikrein levels are negatively associated with the risk of first-ever stroke and stroke recurrence and positively associated with event-free survival during 5 years of follow-up Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
kininogen + H2O Homo sapiens
-
 kinin + bradykinin
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
kininogen + H2O
-
 Homo sapiens kinin + bradykinin
-
 ?

Expression

Organism Comment Expression
Homo sapiens blood plasma tissue kallikrein levels are significantly lower in stroke patients, especially those with ischemic stroke down