Literature summary for 3.4.21.35 extracted from

Christiansen, S.C.; Eddleston, J.; Bengtson, S.H.; Jenkins, G.R.; Sarnoff, R.B.; Turner, R.B.; Gwaltney, J.M.; Zuraw, B.L.
Experimental rhinovirus infection increases human tissue kallikrein activation in allergic subjects (2008), Int. Arch. Allergy Immunol., 147, 299-304.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	experimental rhinovirus infection in allergic asthmatic subjects is accompanied by increased lower airway human tissue kallikrein activation	Homo sapiens

Application

Application	Comment	Organism
medicine	rhinovirus-induced human tissue kallikrein activation may contribute to airway inflammation and asthmatic exacerbations	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bronchoalveolar lavage fluid	-	Homo sapiens	-
nasal mucosa	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-Val-Leu-Arg-4-nitroanilide + H2O	-	Homo sapiens	D-Val-Leu-Arg + 4-nitroaniline	-	?

Synonyms

Synonyms	Comment	Organism
KLK1	-	Homo sapiens
urinary kallikrein	-	Homo sapiens

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Release 2023.1 (January 2023)