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BRENDA support

Literature summary for 3.4.21.35 extracted from

  • Pizard, A.; Richer, C.; Bouby, N.; Picard, N.; Meneton, P.; Azizi, M.; Alhenc-Gelas, F.
    Genetic deficiency in tissue kallikrein activity in mouse and man: effect on arteries, heart and kidney (2008), Biol. Chem., 389, 701-706.
    View publication on PubMed

Application

Application Comment Organism
medicine KLK1 plays a critical role in arterial function, KLK1 is also involved in the control of ionic transport in the renal tubule, there are cardio- and nephroprotective effects of KLK1 and kinins in acute cardiac ischemia, post-ischemic heart failure, and diabetes Homo sapiens

Protein Variants

Protein Variants Comment Organism
R53H inactive Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
KLK1
-
Homo sapiens