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Literature summary for 3.4.21.35 extracted from

  • Saedi, M.S.; Zhu, Z.; Marker, K.; Liu, R.S.; Carpenter, P.M.; Rittenhouse, H.; Mikolajczyk, S.D.
    Human kallikrein 2 (hK2), but not prostate-specific antigen (PSA), rapidly complexes with protease inhibitor 6 (PI-6) released from prostate carcinoma cells (2001), Int. J. Cancer, 94, 558-563.
    View publication on PubMed
Search for more literature for 3.4.21.35

Application

Application Comment Organism
medicine enzyme complexed with prostate protease inhibitor-6 may be a naturally occuring marker of tissue damage and necrosis associated with neoplasia Homo sapiens
medicine enzyme is a diagnostic marker for prostate cancer Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
protease inhibitor-6 from prostate, increased expression in prostate carcinoma; intracellular serine protease inhibitor with both antitrypsin and antichymotrypsin activity; rapid complex formation with the enzyme, involved in neoplastic progression Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular secretion Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Homo sapiens
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
prostate cancer cell increased expression Homo sapiens
-
prostate gland
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polypeptide + H2O
-
 Homo sapiens peptides
-
 ?

Synonyms

Synonyms Comment Organism
K2
-
 Homo sapiens