Crystallization (Comment) | Organism |
---|---|
enzyme expressed in a deglycosylated form at high levels in Pichia pastoris, structure analysis | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
Y228A | enlarges the S1 pocket | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | Zn2+-dependent small-molecule competitive inhibitor | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | involved in blood pressure regulation and inflammation processes | ? | - |
? | |
polypeptide + H2O | Homo sapiens | - |
peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
enzyme expressed in a deglycosylated form at high levels in Pichia pastoris | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | involved in blood pressure regulation and inflammation processes | Homo sapiens | ? | - |
? | |
polypeptide + H2O | - |
Homo sapiens | peptides | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0033 | - |
Zn2+-dependent small-molecule competitive inhibitor | - |
Homo sapiens |