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Literature summary for 3.4.21.35 extracted from

  • Geiger, R.; Miska, W.
    Human tissue kallikrein (1988), Methods Enzymol., 163, 102-115.
    View publication on PubMed
Search for more literature for 3.4.21.35

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular secretion Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Homo sapiens
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
intestine small and large Homo sapiens
-
kidney
-
 Homo sapiens
-
pancreas
-
 Homo sapiens
-
prostate gland
-
 Homo sapiens
-
salivary gland
-
 Homo sapiens
-
seminal plasma
-
 Homo sapiens
-
urine
-
 Homo sapiens
-

Storage Stability

Storage Stability Organism
-30°C, purified urinary enzyme, stable for 1 year Homo sapiens
20°C, purified urinary enzyme, 0.02% w/v NaN3, neutral pH, stable for more than 14 days Homo sapiens
4°C, purified urinary enzyme, 0.02% w/v NaN3, stable for more than 6 months Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-Val-Leu-Arg-p-nitroanilide + H2O
-
 Homo sapiens D-Val-Leu-Arg + p-nitroaniline
-
 ?
kininogen + H2O
-
 Homo sapiens kinin + ?
-
 ?
low-molecular-weight kininogen + H2O
-
 Homo sapiens kallidin + kinin
-
 ?
N-alpha-acetyl-Phe-Arg ethyl ester + H2O
-
 Homo sapiens N-alpha-acetyl-Phe-Arg + ethanol
-
 ?
polypeptide + H2O
-
 Homo sapiens peptides
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Stability

pH Stability pH Stability Maximum Comment Organism
2
-
 immediate irreversible inactivation Homo sapiens