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Literature summary for 3.4.21.34 extracted from

  • Govers-Riemslag, J.W.; Smid, M.; Cooper, J.A.; Bauer, K.A.; Rosenberg, R.D.; Hack, C.E.; Hamulyak, K.; Spronk, H.M.; Miller, G.J.; ten Cate, H.
    The plasma kallikrein-kinin system and risk of cardiovascular disease in men (2007), J. Thromb. Haemost., 5, 1896-1903.
    View publication on PubMed
Search for more literature for 3.4.21.34

Inhibitors

Inhibitors Comment Organism Structure
C1 esterase inhibitor
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor XI + H2O Homo sapiens proteolytic activation activated factor XI + ?
-
 ?
factor XII + H2O Homo sapiens proteolytic activation activated factor XII + ?
-
 ?
additional information Homo sapiens the enzyme is part of the plasma kallikrein-kininogen-kinin system, PKKS, which is involved in cardiovascular disease and artherothrombosis, e.g. coronary heart disease and stroke in middle-aged men, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor XI + H2O proteolytic activation Homo sapiens activated factor XI + ?
-
 ?
factor XII + H2O proteolytic activation Homo sapiens activated factor XII + ?
-
 ?
additional information the enzyme is part of the plasma kallikrein-kininogen-kinin system, PKKS, which is involved in cardiovascular disease and artherothrombosis, e.g. coronary heart disease and stroke in middle-aged men, overview Homo sapiens ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens