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BRENDA support

Literature summary for 3.4.21.34 extracted from

  • Ravindran, S.; Grys, T.E.; Welch, R.A.; Schapira, M.; Patston, P.A.
    Inhibition of plasma kallikrein by C1-inhibitor: role of endothelial cells and the amino-terminal domain of C1-inhibitor (2004), Thromb. Haemost., 92, 1277-1283.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
C1-inhibitor activation of plasma kallikrein and generation of bradykinin are responsible for the angioedema attacks observed with C-1 inhibitor deficiency. C1-inhibitor concentration of greater than 0.001 mM is needed to inhibit 3 nM kallikrein Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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