Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Bauhinia ungulata factor Xa inhibitor protein | - |
Homo sapiens | |
Bauhinia variegata trypsin inhibitor protein | - |
Homo sapiens | |
o-aminobenzoyl-FESPLRINIIKE-N-(2,4-dinitrophenyl)-ethylene diamine | competitive inhibitors, based on the Bauhinia bauhinioides inhibitor protein reactive site sequence | Homo sapiens | |
o-aminobenzoyl-RPGLPVRFESPL-N-(2,4-dinitrophenyl)-ethylene diamine | competitive inhibitors, based on the Bauhinia bauhinioides inhibitor protein reactive site sequence | Homo sapiens | |
specific serine protease inhibitor protein from Bauhinia bauhinioides seeds | Kunitz type, purified 20 kDa protein | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00043 | - |
o-aminobenzoyl-VMIAALPRTMFIQ-N-(2,4-dinitrophenyl)-ethylene diamine | pH 8.0, 37°C | Homo sapiens | |
0.00142 | - |
o-aminobenzoyl-VVISALPRTMFIQ-N-(2,4-dinitrophenyl)-ethylene diamine | pH 8.0, 37°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | plasma | Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
kininogen + H2O | - |
Homo sapiens | bradykinin + fragment of kininogen | - |
? | |
additional information | no activity with o-aminobenzoyl-RPGLPVRFESPL-N-(2,4-dinitrophenyl)-ethylene diamine and o-aminobenzoyl-FESPLRINIIKE-N-(2,4-dinitrophenyl)-ethylene diamine, which are based on the Bauhinia bauhinioides inhibitor protein reactive site sequence | Homo sapiens | ? | - |
? | |
o-aminobenzoyl-VMIAALPRTMFIQ-N-(2,4-dinitrophenyl)-ethylene diamine + H2O | low activity, substrate sequence is based on the Bauhinia ungulata inhibitor protein reactive site sequence | Homo sapiens | ? | - |
? | |
o-aminobenzoyl-VVISALPRTMFIQ-N-(2,4-dinitrophenyl)-ethylene diamine + H2O | substrate sequence is based on the Bauhinia variegata inhibitor protein reactive site sequence | Homo sapiens | ? | - |
? | |
RPGLPVRFESPLRINIIKE + H2O | peptide based on the reactive site of the Bauhinia bauhinioides inhibitor protein, similar to the kinin moiety in human kininogen | Homo sapiens | RPGLPVRFESPLR + INIIKE | main products | ir | |
RPGLPVRFESPLRINIIKE + H2O | peptide based on the reactive site of the Bauhinia bauhinioides inhibitor protein, similar to the kinin moiety in human kininogen | Homo sapiens | RPGLPVR + FESPLRINIIKE | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.01 | - |
o-aminobenzoyl-VMIAALPRTMFIQ-N-(2,4-dinitrophenyl)-ethylene diamine | pH 8.0, 37°C | Homo sapiens | |
3.13 | - |
o-aminobenzoyl-VVISALPRTMFIQ-N-(2,4-dinitrophenyl)-ethylene diamine | pH 8.0, 37°C | Homo sapiens | |
3.66 | - |
o-aminobenzoyl-VVISALPRTMFIQ-N-(2,4-dinitrophenyl)-ethylene diamine | pH 8.0, 37°C | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
assay at | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00000035 | - |
specific serine protease inhibitor protein from Bauhinia bauhinoides seeds | pH 8.0, 37°C | Homo sapiens | |
0.0000069 | - |
Bauhinia ungulata factor Xa inhibitor protein | pH 8.0, 37°C | Homo sapiens | |
0.000023 | - |
Bauhinia variegata trypsin inhibitor protein | pH 8.0, 37°C | Homo sapiens |